Research Associate – (Los Angeles, California, United States)

The University of Southern California (USC), founded in 1880, is located in the heart of downtown L.A. and is the largest private employer in the City of Los Angeles.  As an employee of USC, you will be a part of a world-class research university and a member of the “Trojan Family,” which is comprised of the faculty, students, and staff that make the university what it is.

The USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, Titus Family Department of Clinical Pharmacy is seeking a Research Associate.

The Research Associate is expected to work independently under the direction of Dr. Stan Louie and in close collaboration/consultation with other research lab staff.  This research project combines drug screening using both molecular and cellular models. In addition, animal studies will be performed in acute toxicity and efficacy studies.  The pharmacokinetics of these compounds will be analyzed using LC-MS, where the research associated will need to acquire the raw data analyzed using pharmacokinetic modeling to producing a final result report. All duties will be conducted in accordance with good laboratory practice (GLP) policies and procedures.

Job Accountabilities

  • Plans, designs and conducts highly technical and complex research projects independently and in consultation with supervisor.
  • Identifies, researches, compiles and evaluates data sources, background information and/or technology related to area of specialization.
  • Maintain and conduct research experiments in accordance with laboratory and safety protocols.
  • Analyzes and evaluates research data utilizing computers and provides interpretations requiring significant knowledge of a specialized area of research.
  • Searches literature, utilizing all available resources including electronic, regarding new methodology and designs experiments accordingly.
  • Develop and use HPLC and UHPLC methods to characterize human lipids, proteins, as well as pharmaceutical drug products and metabolites.
  • Conduct research experiments involving animals, including tumor and drug administration and tissue harvesting. Tissues will be harvested and analyzed using histological evaluation, microscopy, and immunohistochemistry. 
  • Supervises the maintenance and calibration of HPLC-MS equipment
  • Develop and validate GLP assays.
  • Supervises the laboratory activities and compliance measure mandated by the University.
  • Ensure the maintenance of laboratory notebook and record keeping for all staff and student members of the laboratory.
  • Work on HPLC and clinical sample preparation.
  • Work on LC-MS.
  • Assist in the preparation of grant proposals, but is not responsible for generating grant funds.
  • Participate in publications and poster presentations.
  • Participate in lab meetings and responsible for preparing a weekly report.  
  • Performs other related duties as assigned or requested. The University reserves the right to add or change duties at any time.

Preferred Qualifications and Experience

  • Doctorate degree in area directly related to field of research specialization
  • Experience in LCMS required.
  • Experience in drug development and screening.
  • Able to perform molecular dissection assays (e.g., Western blots, RT-PCR, immunofluorescent staining)
  • Experience in animal handling and administration of drugs to animal models
  • Highly motivated and works independently on research projects
  • More than 3 years of LCMS experience.
  • Western and RT-PCR experience.
  • Designs experiments independently within areas of expertise.
  • Follows experimental protocols and procedures, including detailed data collection and analysis.
  • Knowledge of safety standards and protocols.
  • Knowledge of maintenance of HPLC equipment.
  • Working knowledge of laboratory equipment and research protocols.
  • Knowledge of GLP policies and procedures and record keeping.
  • Knowledge of computer analysis techniques and ability to provide routine analysis and interpretation of research data.
  • 5 years in a research lab setting.
  • 3 years in HPLC.
  • 5 years in mammalian cell culture.

The annual base salary range for this position is $66,000 – $67,000. When extending an offer of employment, the University of Southern California considers factors such as (but not limited to) the scope and responsibilities of the position, the candidate’s work experience, education/training, key skills, internal peer equity, federal, state, and local laws, contractual stipulations, grant funding, as well as external market and organizational considerations.

Minimum Education: Ph.D. or equivalent doctorate
Minimum Experience: 1 year
Minimum Field of Expertise: Directly related education and experience in research specialization with advanced knowledge of equipment, procedures and analysis methods.

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